Latest App Notes & Case Studies

Lipid profiling from complex lipid extracts can be a challenging and time-consuming task. The high complexity of samples and co-elution of isobaric or isomeric compounds complicate the confident annotation of lipids.

Pyruvate kinase is an enzyme involved in energy-supplying glycolysis and ATP synthesis, thus is pivotal for the eucaryotic energy metabolism. In addition, overexpression of pyruvate kinase is believed to play a role in cancer.

Identifying a respiratory viral infection can be challenging with different families of viruses being indistinguishable during the acute phase of illness, despite the outcome and long-term prognosis of the infection being different. The ability to diagnose a respiratory virus at the initial stage of infection can result in more effective treatment for the patient.

Read how scientists at Merck KGaA use light scattering measurements to predict how formulations will behave at clinically relevant concentrations and find the optimal formulation buffer for their biologics candidates.

Gas chromatography-mass spectrometry (GC-MS) is regarded as the select analytical technique for the analysis of semivolatile organic compounds (SVOCs) in environmental matrices.

Histamine is a molecule that plays a major role in local immune responses, produced and released by basophils and mast cells as part of the inflammatory response to a foreign body.

There is a growing demand for more rapid methods with maintained robustness and chromatographic performance for the identification and quantitation of chemical residues in food analysis.

The increasing global demand for food has led to a growing use of pesticides, resulting in elevated risks of trace level chemical pollutants in food. Rapid and reliable methods are required to identify and quantify these pollutants with high sensitivity and over a wide dynamic range.

Download this app note to discover a method that can reduce the risk of cross-contamination, easily automate a process that was previously open to human error as well as increase assay confidence by ensuring sample integrity.

One of the major challenges faced by most toxicology laboratories is analyzing hundreds of drugs of abuse in biological samples. This is further complicated by the constantly increasing emergence in the volume of designer and illicit drugs.