Simple and Fast Tracking of Drug–Antibody Ratio Distribution

Antibody drug conjugates (ADCs) are biotherapeutics, composed of small molecule drugs conjugated to an antibody scaffold, that have very complex molecular structures. The information about the average drug antibody ratio (DAR) is essential for assessing ADC qualities and so DAR values are one of the critical quality attributes (CQAs) for the therapeutic index of ADCs.

Download this app note to learn about an intact multiple attribute methodology workflow for DAR monitoring that:

• Allows DAR monitoring for a large sample set
• Provides powerful product attribute definition, tracking and quantification
• Is streamlined and compliance-ready