Liquid Chromatography – Webinars and Online Events

In this webinar, our expert speakers will focus on various gene editing systems and how you can utilize analytical instrumentation to characterize the various components.

Studies on drug metabolism aid in evaluating the pharmacokinetics, pharmacodynamics and safety during discovery and development.

During this webinar, you will discover ways to improve your protein extraction, such as by reducing workflow complexity, improving results from scarce samples, setting up robust assays and working with large sample cohorts.

Watch this webinar to discover an EAD platform method that enables confident and accurate identification, accurately quantify and monitor quality attributes
and can do all the above with MAM in a single injection.

Speaking at the Advances in Drug Discovery & Development 2022 online symposium, Adam Crowe from SCIEX discussed how an ionizable lipid was analyzed with liquid chromatography coupled with mass spectrometry.

在这个网络研讨会,您将了解capillary electrophoresis (CE) and LC-MS are being used to ensure vaccine and cell and gene therapy product quality. We will discuss how LC-MS is being used to identify impurities present in lipid nanoparticle (LNP) vaccines that have been found to deactivate mRNA. We will also cover how CE is being used in viral vector production to ensure product quality.

Analyzing lipids can be a challenge but combining tandem mass spectra obtained from electron-activated dissociation (EAD) can make the process easier. In fact, over 1000 lipids can be analyzed by ballistic data-dependent acquisition liquid chromatography-mass spectrometry. This methodology produces a large number of high-quality EAD fragmented spectra, making annotation the limiting factor, but combinatorial fragmenters can be used to effectively solve this challenge.

In this webinar, we demonstrate how the ZenoTOF 7600 system can be used in a workflow for the routine analysis of lipids that enables the resolution of sn-isomerism and double bond positions from high-throughput EAD mass spectrometry data.

Speaking at Proteomics & Metabolomics 2022, Prof. Gérard Hopfgartner and
David Ruskic, PhD from University of Geneva, presented their talk on direct analysis of complex biological fluids such as, plasma and urine with liquid chromatography.

Speaking at Proteomics & Metabolomics 2022, Mohit Jain from Bruker, presented their talk on small molecule biomarkers in drug development.

In this webinar you will gain a deeper understanding of how to measure oligonucleotide in a robust environment with high isotopic fidelity mass spectrometry and much more.